| Title | Platform | Year | Company | Composer |
| Earth & Beyond | PC | 2002 | Westwood Studios | Frank Klepacki, David Arkenstone |
| Ecco the Dolphin | GEN | 1993 | Novotrade / Sega | Spencer Nilsen, Brian Coburn, András Magyari |
| Ecco the Dolphin | SCD | 1993 | Sega | Spencer Nilsen |
| Ecco the Dolphin: Defender of the Future | DC, PS2 | 2000 | Appaloosa / Sega | Tim Follin, Attila Héger |
| Ecco: The Tides of Time | SCD | 1994 | Sega | Spencer Nilsen |
| Echelon: Wind Warriors | PC | 2002 | MADia Entertainment | Vazha Bzikadze |
| Emperor: Battle for Dune | PC | 2001 | Westwood Studios | Frank Klepacki, David Arkenstone, Jarrid Mendelson |
| End of Twilight | PC | 2001 | Craftpath | Sergey Perminov |
| Equinox | SNES | 1993 | Software Creations | Tim Follin, Geoff Follin |
| Escape From Coldtitz | AMI | 1991 | Digital Magic | Bjørn Lynne |
| Escape from Monkey Island | PC, PS2 | 2000 | LucasArts Entertainment | Clint Bajakian, Anna Karney, Michael Land, Peter McConnell |
| Evasive Action | PC | 1993 | Atreid / Software Toolworks | Frédéric Motte, Mark Knight |
| EverQuest Online Adventures | PS2 | 2003 | Sony Online Entertainment | Jeremy A. Bell, Robert King, Paul Romero, Jeremy Soule |
| EverQuest Online Adventures: Frontiers | PS2 | 2003 | Sony Online Entertainment | Jeremy A. Bell, Robert King, Paul Romero, Jeremy Soule, Keith Arem, Joe Hight |
| Evolution: The Game of Intelligent Life | PC | 1997 | Crossover Technologies | Patrick Zimmerli |
| Extase | AMI | 1990 | Cryo | Stéphane Picq, Philippe Eidel & Arnaud Devos |
| Extreme Roller | PSX, N64 | 2001 | Microids | Jake Kaufman |
| Extreme-G | N64 | 1997 | Probe Entertainment | Simon Robertson, Stephen Root |
| Extreme-G 2 | N64, PC | 1998 | Probe Entertainment | Simon Robertson, Stephen Root |
| Eye of the Beholder II: The Legend of Darkmoon | PC | 1991 | Westwood Studios | Frank Klepacki |